2021 Mercedes-Benz E 350

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2021 Mercedes-Benz E 350
RENDERED 2026-08-02T12:23:12.545Z

Only 12 complaints on file — too few for a fair verdict.

This verdict reflects complaint volume compared to this model's typical year. Recalls and safety issues below apply regardless of the verdict — always check them.

Only 12 complaints on file — too few for a fair verdict. The data below is complete but unranked.

How is this computed?

COMPLAINTS PER YEAR

Complaints per year, Mercedes-Benz E 350 Bar chart of distinct NHTSA complaints filed per model year, 2021 highlighted. 2020: 8 complaints 2020 2021: 12 complaints 2021 2022: 7 complaints 2022 2023: 5 complaints 2023 2024: 5 complaints 2024 2025: 2 complaints 2025 2026: 0 complaints 2026
2021: 12 complaints
View as data table
YearComplaints
20208
202112
20227
20235
20245
20252
20260

KNOWN PROBLEM AREAS

Only 12 complaints on file for this model year -- too few to rank by share. Raw counts only, below.

ENGINE

4 of 12 total reports mention: engine.

FIRE
Show complaint excerpts

FIRE FIRE FIRE Information light came on just saying 12 Volt Battery. I sat in the car letting it idle for about 3 minutes. It began to smoke and then burst into flames.

NHTSA ODI report, 20241207

ELECTRICAL SYSTEM

4 of 12 total reports mention: electrical system.

FIRE
Show complaint excerpts

FIRE FIRE FIRE Information light came on just saying 12 Volt Battery. I sat in the car letting it idle for about 3 minutes. It began to smoke and then burst into flames.

NHTSA ODI report, 20241207

POWER TRAIN

2 of 12 total reports mention: power train.

FUEL/PROPULSION SYSTEM

2 of 12 total reports mention: fuel/propulsion system.

BACK OVER PREVENTION

2 of 12 total reports mention: back over prevention.

Show complaint excerpts

When in reverse, sometimes the rearview camera image does not come and and the parking sensors do not work.

NHTSA ODI report, 20231219

SAFETY TIMELINE

R 20201218 — seats

Mercedes-Benz USA, LLC. (MBUSA) is recalling certain 2021 E350 and E450, 2019-2021 AMG E53 and 2020-2021 AMG E63 vehicles.

Remedy: MBUSA will notify owners, and dealers will inspect for the mechanical seat adjustment range limitation for the front passenger seat and install it if necessary, free of charge. The recall began December 18, 2020.

Campaign 20V673000 — check if this car was fixed

R 20210312 — communication, electrical system

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2016 - 2021 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, GT-Class, C-Class, E-Class, S-Class, CLS-Class, SL-Class, B-Class, GLB-Class, GLC-Class, and G-Class vehicles.

Remedy: MBUSA will notify owners, and the communication module software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. The recall began March 12, 2021. Owners may contact MBUSA customer service at 1-877-762-8267.

Campaign 21V058000 — check if this car was fixed

R 20210408 — back over prevention

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, and AMG E63 vehicles. The parking control unit may fail to display the rearview camera image and cause the parking sensors to misidentify or fail to detect objects.

Remedy: All affected vehicles are still within MBUSA's control. MBUSA will replace the parking control unit, free of charge. The recall began April 8, 2021. Owner may contact MBUSA customer service at 1-800-367-6372.

Campaign 21V228000 — check if this car was fixed

R 20210429 — seats

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 E350, E450, E450 Wagon, E63S AMG, 2020 E63S AMG Wagon, and 2020-2021 E53 AMG vehicles. The passenger seat limiter may allow the seat to be positioned too close to the air bag.

Remedy: MBUSA will notify owners, and dealers will recalibrate the passenger seat limiter, free of charge. The recall began April 29, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040002.

Campaign 21V216000 — check if this car was fixed

R 20210521 — air bags, seat belts, seats

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 C-Class, E-Class, E-Class Coupe and Convertible, GLC, CLS, AMG GT 4-door Coupe and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle model details.

Remedy: MBUSA will notify owners, and dealers will replace the seat position switches, free of charge. Owner letters were mailed May 21, 2021. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2021040016.

Campaign 21V230000 — check if this car was fixed

R 20210628 — back over prevention, electrical system

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2019-2021 CLA-Class, GLE/GLS-Class, A-Class, E-Class, E-Class Coupe and Convertible, GLA/GLB-Class, GLC-Class, CLS-Class, and AMG GT-Class 4-door Coupe vehicles.

Remedy: The multimedia system software will be updated by a dealer, or through an over-the-air (OTA) update, free of charge. Owner notification letters were mailed beginning June 28, 2021. Owners may contact MBUSA customer service at 1-800-367-6373.

Campaign 21V354000 — check if this car was fixed

R 20210903 — air bags

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021 CLS450, AMG E53, AMG CLS53, E350, E450, AMG GT43, AMG GT53, 2020 S450, S560, G550, AMG GLC63, 2020-2021 GLC300, and AMG G63 vehicles.

Remedy: Dealers will inspect and replace as necessary, the side impact crash sensors, free of charge. Owner notification letters were mailed on September 3, 2021. Owners may contact MBUSA customer service at 1-800-367-6372.

Campaign 21V527000 — check if this car was fixed

R 20210924 — seat belts

Mercedes-Benz, LLC (MBUSA) is recalling certain 2021 G550, AMG G63, E350, E450, AMG CLS53, AMG E53, AMG GT43, AMG GT53, AMG GT63, 2021-2022 CLS450, and AMG E63 vehicles.

Remedy: Dealers will inspect, and replace as necessary, the rear seat belt assemblies, free of charge. Owners notified of the voluntary recall campaign by an interim letter on August 13, 2021. A final letter was mailed on September 24, 2021.

Campaign 21V483000 — check if this car was fixed

R 20220509 — steering

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2022 C-Class, E-Class, S-Class, SL, EClass Coupe/Convertible, CLS, AMG GT 4-doors Coupe, and EQS vehicles with a heated leather steering wheel.

Remedy: Dealers will update the hand detection control unit software for the DISTRONIC system, free of charge. Owner notification letters were mailed May 6, 2022. Owners may contact MBUSA customer service at 1-800-367-6372.

Campaign 22V189000 — check if this car was fixed

R 20220708 — communication, electrical system

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2017-2022 CLA-Class, GLA-Class, GLE-Class, GLS-Class, SLC-Class, A-Class, AMG GT-Class, C-Class, E-Class, S-Class, SL-Class, GLC-Class, CLS-Class, GLB-Class, and G-Class vehicles.

Remedy: The communication module software will be updated through an Over-the-Air (OTA) update or by a dealer, free of charge. Owner notification letters were mailed July 8, 2022.

Campaign 22V365000 — check if this car was fixed

R 20220715 — back over prevention

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2018-2021 CLA-Class, GLE/GLS-Class, A-Class, C-Class, E-Class, E-Class Coupe/Convertible, GLA/GLB-Class, GLC-Class, and CLS-Class vehicles.

Remedy: Dealers will update the rearview camera software, free of charge. Owner notification letters were mailed July 15, 2022. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2022060007.

Campaign 22V232000 — check if this car was fixed

R 20230929 — fuel system, gasoline

Mercedes-Benz USA, LLC (MBUSA) is recalling certain 2021-2023 C-Class, E-Class, S-Class, CLS, SL, GT, GLC, GLE, GLS, and G-Class vehicles. Please refer to MBUSA's recall report for specific vehicle details.

Remedy: Dealers will replace the fuel pump, free of charge. Owner notification letters were mailed on June 14, 2024. Owners may contact MBUSA customer service at 1-800-367-6372. MBUSA's number for this recall is 2023070012.

Campaign 23V445000 — check if this car was fixed

BUY-SMART CHECKLIST

2021 Mercedes-Benz E 350 — pre-purchase inspection

  • Test/inspect for engine issues (4 reports on file for this year).
  • Test/inspect for electrical system issues (4 reports on file for this year).
  • Test/inspect for power train issues (2 reports on file for this year).
  • Verify recall 20V673000 (seats) has been completed.
  • Verify recall 21V058000 (communication, electrical system) has been completed.
  • Verify recall 21V228000 (back over prevention) has been completed.
  • Verify recall 21V216000 (seats) has been completed.
  • Verify recall 21V230000 (air bags, seat belts, seats) has been completed.
  • Verify recall 21V354000 (back over prevention, electrical system) has been completed.
  • Verify recall 21V527000 (air bags) has been completed.
  • Verify recall 21V483000 (seat belts) has been completed.
  • Verify recall 22V189000 (steering) has been completed.
  • Verify recall 22V365000 (communication, electrical system) has been completed.
  • Verify recall 22V232000 (back over prevention) has been completed.
  • Verify recall 23V445000 (fuel system, gasoline) has been completed.

FAQ

Is the 2021 Mercedes-Benz E 350 reliable?

There isn't enough NHTSA complaint data on file yet to give this model year a verdict.

What are the most common problems with the 2021 Mercedes-Benz E 350?

The most-reported component is engine, accounting for 33% of complaints on file.

How many recalls does the 2021 Mercedes-Benz E 350 have?

12 recalls on file for this model year.

Data updated 2026-07-11 · Complaints are unverified owner reports filed with NHTSA, not independently verified defects. Methodology.